文献：突触结合蛋白2抗体应用方法

中文名称    突触结合蛋白2抗体    

英文名称    EF-CBP2    

别    名    EF hand calcium binding protein 2; EF-hand calcium-binding protein 2; N-terminal EF-hand calcium-binding protein 2; NECA2_HUMAN; Necab2; EFCBP2; EF CBP2; Neuronal calcium binding protein 2; Neuronal calcium-binding protein 2; Stip 2; Stip-2; Stip2; Synaptotagmin interacting protein 2; Synaptotagmin-interacting protein 2.    

供 应 商    远慕生物

研究领域    细胞生物  免疫学  神经生物学  结合蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）突触结合蛋白2抗体
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    43kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human EF-CBP2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

突触结合蛋白2抗体产品介绍    background:

Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Subcellular Location:
Cytoplasm (By similarity).

Tissue Specificity:
Expressed in brain

Similarity:
Contains 1 ABM domain.
Contains 2 EF-hand domains.

Database links:

Entrez Gene: 54550 Human

SwissProt: Q7Z6G3 Human

Unigene: 140950 Human


important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.