DNA损伤诱导转录样蛋白4抗体产品应用

中文名称    DNA损伤诱导转录样蛋白4抗体
英文名称    DDIT4L       
别    名    DNA damage inducible transcript 4 like protein; HIF 1 responsive protein RTP801 like; Homolog of mouse SMHS1; Protein regulated in development and DNA damage response 2; REDD 2; REDD2; RTP801L; DDT4L_HUMAN.    
浓    度    0.1ml  0.2ml      
研究领域    细胞生物  免疫学  细胞周期蛋白  转录调节因子      
抗体来源    Rabbit    
克隆类型    Polyclonal    
交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,     
产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 DNA损伤诱导转录样蛋白4抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    
分 子 量    22kDa    
细胞定位    细胞浆     
性    状    Lyophilized or Liquid    
浓    度    1mg/1ml    
免 疫 原    KLH conjugated synthetic peptide derived from human DDIT4L    
亚    型    IgG    
纯化方法    affinity purified by Protein A    
储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    
保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

DNA损伤诱导转录样蛋白4抗体产品介绍    background:
DDIT4L inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. It is up regulated in atherosclerotic plaques relative to healthy segments of the same artery.
Function:
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery.
Similarity:
Belongs to the DDIT4 family.
Database links:
UniProtKB/Swiss-Prot: Q96D03.1
important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.