2948 Angiopoietin-2 Antibody #2948

"上海博耀生物销售Angiopoietin-2 Antibody #2948，CST原装品质，价格优惠，订购Angiopoietin-2 Antibody #2948，详情请咨询销售

"上海博耀生物销售Angiopoietin-2 Antibody #2948，CST原装品质，价格优惠，订购Angiopoietin-2 Antibody #2948，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Angiopoietin-2 Antibody #2948
货号：2948
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2948S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	M	Transfected Only	66	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Angiopoietin-2 Antibody detects transfected levels of mouse angiopoietin-2 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys275 of mouse angiopoietin-2. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Angiopoietins are a family of Tie receptor ligands. There are four angiopoietins discovered so far: angiopoietins 1, 2, 3 and 4 (Ang1, 2, 3, and 4) (1-3). Ang1 binds to the Tie-2 receptor and leads to its autophosphorylation and subsequent activation of downstream signaling pathways. It plays an important role in blood vessel formation, maturation and subsequent stabilization (1,4,5). Ang2 is an endothelium-specific growth factor that functions as an antagonist to Ang1, promotes vascular associated proinflammatory function, destabilizes quiescent endothelium, leads to vascular leakage and vascular destablization and remodeling (2,6,7). Ang2 is selectively expressed in many tumor tissues where, combined with other growth factors such as VEGF, it can promote vascular remodeling, angiogenesis and inflammation (7-9).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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