2937 TP/ECGF1 Antibody #2937

"上海博耀生物销售TP/ECGF1 Antibody #2937，CST原装品质，价格优惠，订购TP/ECGF1 Antibody #2937，详情请咨询销售人员！产品详

"上海博耀生物销售TP/ECGF1 Antibody #2937，CST原装品质，价格优惠，订购TP/ECGF1 Antibody #2937，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：TP/ECGF1 Antibody #2937
货号：2937
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2937S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H	Endogenous	50, 60	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： TP/ECGF1 Antibody detects endogenous levels of human TP/ECGF1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding residues surrounding Gln370 of human TP/ECGF1. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Thymidine phosphorylase (TP) is a platelet-derived endothelial cell growth factor (PD-ECGF) that catalyzes the formation of thymine and 2-deoxy-D-ribose-1-phosphate from thymidine and orthophosphate (1). This intracellular enzyme is capable of both promoting angiogenesis and inhibiting apoptosis. Thymidine phosphorylase catalytic activity is required for its angiogenic function (2,3). Increased expression of TP/PD-ECGF is seen in a wide variety of different solid tumors and inflammatory diseases and is often associated with poor prognosis (4,5). Alternatively, TP can activate fluorouracil derivative (DFUR) prodrugs and increase the antitumor activity of the related treatment (1,5). The use of thymidine phosphorylase as a cancer therapeutic target has been studied extensively, with emphasis on either inhibiting TP enzymatic activity or increasing enzyme induction with concomitant DFUR treatment (1,5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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