2954 Smac/Diablo Mouse mAb #2954

"上海博耀生物销售Smac/Diablo Mouse mAb #2954，CST原装品质，价格优惠，订购Smac/Diablo Mouse mAb #2954，详情请咨询销售人员

"上海博耀生物销售Smac/Diablo Mouse mAb #2954，CST原装品质，价格优惠，订购Smac/Diablo Mouse mAb #2954，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Smac/Diablo Mouse mAb #2954
货号：2954
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： Monoclonal
规格：

No.	Size	Price
2954S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P IF-IC	H Mk	Endogenous	21	Mouse IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Smac/Diablo Mouse mAb detects endogenous levels of processed and unprocessed human Smac/Diablo. The antibody reacts weakly with mouse and rat Smac/Diablo.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a full length peptide corresponding to human Smac/Diablo raised in E-coli.
抗体背景：

Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis (1,2). Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins) (1,2). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases (3,4). This interaction involves mainly the amino-terminal residues of Smac/Diablo with the BIR3 region of XIAP, supplemented with several other hydrophobic interactions between the helical structures of Smac/Diablo and other areas of BIR3 (5,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab104312/Anti-FAM83F antibody
ab100882/Anti-DHX58 antibody
Anti-ROM1视网膜感光细胞外节膜蛋白1抗体
ab103078/Anti-FANCA antibody
ab101764/Anti-DOC2B antibody
Anti-ACE2血管紧张素转换酶2抗体
ab101430/Anti-Cyclin D1 antibody
Anti-Kinesin驱动蛋白KNS1抗体
Anti-G protein beta subunit GIG蛋白/鸟苷酸结合蛋白抗体
ab102544/Anti-E2 230K antibody
Anti-IDE胰岛素降解酶抗体
Anti-GLP-2胰高血糖素样肽-2抗体
ab103152/Anti-Granzyme B antibody
ab10428/Anti-Bad (phospho S112) antibody
ab102978/Anti-B4GALT2 antibody
Anti-Insulin Receptor alpha胰岛素受体α抗体"
本页产品地址：http://www.geilan.com/sell/show-3244723.html