产品简介
"上海博耀生物销售RhoB Antibody #2098,CST原装品质,价格优惠,订购RhoB Antibody #2098,详情请咨询销售人员!产品详细参数如
产品说明
"上海博耀生物销售
RhoB Antibody #2098,CST原装品质,价格优惠,订购
RhoB Antibody #2098,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:RhoB Antibody #2098
货号:2098
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Polyclonal
规格:
| No. |
Size |
Price |
| 2098P |
40 ul (4 western blots) |
询价 |
| 2098S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W |
H M R Mk |
Endogenous |
21 |
Rabbit |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
M=Mouse
R=Rat
Mk=Mon
key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
RhoB Antibody detects endogenous levels of total RhoB protein. The antibody does not cross-react with RhoA or RhoC.
来源及纯化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human RhoB. Antibodies are purified using protein A and peptide affinity chromatography.
抗体背景:
Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins (GAPs), which catalyze the hydrolysis of GTP to GDP. A third level of regulation is provided by the stoichiometric binding of Rho GDP dissociation inhibitor (RhoGDI) (1). RhoA, RhoB and RhoC are highly homologous, but appear to have divergent biological functions. Carboxy-terminal modifications and differences in subcellular localization allow these three proteins to respond to and act on distinct signaling molecules (2,3).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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