2102 Non-phospho-Src (Tyr416) (7G9) Mouse mAb #2102

"上海博耀生物销售Non-phospho-Src (Tyr416) (7G9) Mouse mAb #2102，CST原装品质，价格优惠，订购Non-phospho-Src (Tyr416) (7G

"上海博耀生物销售Non-phospho-Src (Tyr416) (7G9) Mouse mAb #2102，CST原装品质，价格优惠，订购Non-phospho-Src (Tyr416) (7G9) Mouse mAb #2102，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Non-phospho-Src (Tyr416) (7G9) Mouse mAb #2102
货号：2102
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： Monoclonal
规格：

No.	Size	Price
2102P	40 ul (4 western blots)	询价
2102S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP	H M R (C) (X)	Endogenous	60	Mouse IgG2b

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat  C=Chicken  X=Xenopus
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Non-phospho-Src (Tyr416) (7G9) Mouse mAb detects endogenous levels of Src only when dephosphorylated at tyrosine 416. The antibody cross-reacts with other Src family members (Lyn, Fyn, Lck, Yes and Hck) dephosphorylated at equivalent sites.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Tyr416 of human Src.
抗体背景：

The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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