重组人基质细胞来源因子-1b, His标签/SDF 1b Human, His产品编号：CHM-249 产品规格：2g/10g/1mg Catalo

  关于慧嘉

  厦门慧嘉生物科技有限公司，是一家专业代理国内外知名品牌生命科学试剂产品，产品范围涉及细胞生物学，分子生物学，免疫学及生物化学等实验室科学研究试剂，包括细胞系，细胞培养，ELISA和免疫组化抗体，一抗，二抗，单克隆和多克隆抗体，PCR及放免试剂盒，生化试剂以及各类实验仪器。

  公司成立以来，一群有志的年轻人本着始终拥有的创业激情，注重跟踪世界范围分子生物学、细胞生物学等生物学科的发展前沿，努力将欧美专业生产厂家的具有国际先进水平的产品推荐给各类研究人员。已被广泛应用于生命科学基础研究、开发应用、制药、疾病诊断与控制、人口与健康、生物技术等诸多领域。客户遍布大学、研究所、医院、卫生防疫、商品检验检疫、制药公司、生物技术公司和食品工业等单位。

  公司在重视产品质量的同时，也建立了一套集技术支持、物流、售后服务等多个部门的全方位的服务体系，努力把我们方便、快捷、周到的服务提供给每一个客户。

  我们热诚希望与广大用户朋友携手合作，为推动中国的科技发展尽上一份绵薄之力!

  ※ 公司经营宗旨:

  诚信是金、信用第一，努力成为国内外生命科学和生物技术行业的信用企业。

  ※ 公司使命:

  为生命科研工作者和人类健康提供优质的产品和服务，成为您实验身边的好伙伴。

  ※ 价值观:

  忠诚、敢为、勤奋、成功

重组人基质细胞来源因子-1b, His标签/SDF 1b Human, His

Catalogue Number	CHM-249
Synonyms	SDF-1, CXCL12, Pre-B cell growth-stimulating factor, PBSF, hIRH, chemokine (C-X-C motif) ligand 12, SDF1, SDF1B, TPAR1, SCYB12, SDF-1b, TLSF-b, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1, Thymic lymphoma cell-stimulating factor, TLSF.
Introduction	SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). It is produced in two forms, SDF-1?/CXCL12a and SDF-1?/CXCL12b, by alternate splicing of the same gene. Chemokines are characterized by the presence of four conserved cysteines, which form two disulfide bonds. The CXCL12 proteins belong to the group of CXC chemokines, whose initial pair of cysteines are separated by one intervening amino acid. CXCL12 is strongly chemotactic for lymphocytes and has been implicated as an important cell co-ordinator during development. During embryogenesis it directs the migration of hematopoietic cells from foetal liver to bone marrow. Mice which were knocked-out for CXCL12 gene were lethal before the birth or within just 1 hour of life. As another role, CXCL12a alters also the electrophysiology of neurons. CXCL12 was shown to be expressend in many tissues in mice (including brain, thymus, heart, lung, liver, kidney, spleen and bone marrow). The receptor for this chemokine is CXCR4, which was previously called fusin. This CXCL12-CXCR4 interaction used to be considered exclusive (unlike for other chemokines and their receptors), but recently it was suggested that CXCL12 is also bound by CXCR7 receptor. The gene for CXCL12 is located on human chromosome 10. In human and mouse both CXCL12 and CXCR4 show high identity of sequence: 99% and 90%, respectively.
Description	SDF-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 93 amino acids (22-93 a.a.) and having a molecular mass of 10.8 KDa. The SDF-1b is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile filtered colorless solution.
Formulation	The SDF-1 beta His Tag protein contains 20mM Tris-HCl buffer pH-8 and 10% glycerol.
Stability	Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity	Greater than 90% as determined by Analysis by SDS-PAGE.
Sequence	MGSSHHHHHH SSGLVPRGSH MKPVSLSYRC PCRFFESHVA RANVKHLKIL NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKR FKM.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

本页产品地址：http://www.geilan.com/sell/show-2759852.html