二氢叶酸还原酶样1抗体实验简介

中文名称    二氢叶酸还原酶样1抗体
英文名称    DHFRL1        
别    名    DHFRP4; Dihydrofolate reductase like 1; Dihydrofolate reductase pseudogene 4; DYRL1_HUMAN.    
浓    度    0.1ml  0.2ml      
研究领域    肿瘤  细胞生物  信号转导      
抗体来源    Rabbit    
克隆类型    Polyclonal    
交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,     
产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 二氢叶酸还原酶样1抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    
分 子 量    21kDa    
细胞定位    细胞浆 细胞膜     
性    状    Lyophilized or Liquid    
浓    度    1mg/1ml    
免 疫 原    KLH conjugated synthetic peptide derived from human DHFRL1    
亚    型    IgG    
纯化方法    affinity purified by Protein A    
储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    
保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
   
二氢叶酸还原酶样1抗体产品介绍    background:
May play a role in folate metabolism. Belongs to the dihydrofolate reductase family.
Function:
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.
Subcellular Location:
Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Tissue Specificity:
Expressed in numerous cell lines.
Similarity:
Belongs to the dihydrofolate reductase family.
Contains 1 DHFR (dihydrofolate reductase) domain.
Database links:
Entrez Gene: 200895 Human
SwissProt: Q86XF0 Human
Unigene: 718516 Human