组织蛋白酶E抗体应用方法

英文名称：Anti-Cathepsin E
中文名：组织蛋白酶E抗体
别名：Cathepsin E; CATE; CTSE; EC 3.4.23.34; Erythrocyte membrane aspartic proteinase.
规格：0.1ml/100μg,0.2ml/200μg
交叉反应：hu, rat, mo
产品类型：一抗
应用领域:/合成与降解
蛋白分子：predicted molecular weight: 42kDa
浓度值：1mg/1ml
物理性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human Cathepsin E C-terminus
亚型：polyclonal
纯化方法：affinity purified by Protein A
保存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
应用技术：//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
保存环境：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

产品介绍：Cathepsin E is an intracellular aspartic protease of the pepsin family, which is structurally highly homologous to the lysosomal aspartic protease cathepsin D. Cathepsin E is less abundant than Cathepsin D ａnd has a more limited distribution, which includes lymphoid tissues, gastrointestinal tract tissue, blood cells, microglia ａnd activated B lymphocytes. It is not expressed in resting B lymphocytes. Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. It may also play a role in activation-induced lymphocyte depletion in the thymus, ａnd in neuronal degeneration ａnd glial cell activation in the brain.