| 提交询价信息 |
| 发布紧急求购 |
价格：电议
所在地：北京
型号：96T
更新时间：2024-04-22
浏览次数：1458
公司地址：北京市海淀区厢黄旗2号楼1层4-179室
李小姐(女士)
|
骨生化标志物ELISA试剂盒详细介绍：
一.Anti-Human PTH (1-34) Antibody ELISA KitINTENDED USE This kit is intended for research use only in the qualitative detection of antibodies to human PTH (1-34) in humans or other animal models. Reference ranges and clinical utility have not been established. 二.Anti-Human PTH (1-34) Antibody ELISA Kit INTRODUCTION (rhPTH 1-34) is a recombinant human parathyroid hormone derivative consisting of the first 34 amino acids of the hormone. Teriparatide was approved as a drug by the FDA in 2002 and is sold by Eli Lilly & Co. under the brand name Forteo. Teriparatide is indicated for use in patients with osteoporosis. It is currently administered by injection and has an anabolic effect on bone, binding to the PTH/PTHrp Type 1 receptor with the same affinity as the intact molecule, PTH (1-84). This receptor activation results in a series of events leading to the formation of new trabecular and cortical bone. Research is continuing at pharmaceutical and biotech companies to pursue similar drugs and alternate delivery pathways.Immunogenicity for this drug, defined as the presence of antibodies to human PTH (1-34), was detected in 2.8% of women receiving teriparatide during the clinical trials of Forteo. The detection of these circulating antibodies may be of clinical relevance for the proper assessment of patients. |
免责声明：以上所展示的[96T 人甲状旁腺激素1-34 ELISA试剂盒]信息由会员[北京科瑞美科技有限公司]自行提供，内容的真实性、准确性和合法性由发布会员负责。
