3248 PKG-1 (C8A4) Rabbit mAb #3248

"上海博耀生物销售PKG-1 (C8A4) Rabbit mAb #3248，CST原装品质，价格优惠，订购PKG-1 (C8A4) Rabbit mAb #3248，详情请咨询销售

"上海博耀生物销售PKG-1 (C8A4) Rabbit mAb #3248，CST原装品质，价格优惠，订购PKG-1 (C8A4) Rabbit mAb #3248，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：PKG-1 (C8A4) Rabbit mAb #3248
货号：3248
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
3248S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W	H M R Mk	Endogenous	78	Rabbit IgG

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： PKG-1 (C8A4) Rabbit mAb detects endogenous levels of total PKG-1 protein, including both α and β isoforms. The antibody does not cross-react with PKG-2.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to cental residues of human PKG-1.
抗体背景：

Cyclic GMP-dependent kinases (cGK/PKG) belong to the AGC family of serine/threonine protein kinases. In mammals, two genes encode PKG-1 and PKG-2. Alternative PKG-1 splicing yields α and β isoforms, which display tissue-specific expression patterns in humans (1). All PKG family members are activated by increased cellular cGMP, which binds to the enzyme's regulatory domain inducing a conformational change and leading to enzyme activation. cGMP levels are increased through the activation of guanylyl cyclases, a process known to occur in part through nitric oxide (NO) signaling (2).In addition to well established roles in platelet activation and smooth muscle relaxation (3), PKG signaling is important in many biological processes including cardiac contractility, axon guidance, bone growth, contraction of intestinal smooth muscle and erectile dysfunction (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab103667/Anti-beta II Tubulin antibody
ab101866/Anti-Contactin 1 antibody
Anti-CNTNAP4接触蛋白相关蛋白4抗体
Anti-Adiponectin Receptor 1脂联素受体1抗体
Anti-Calponin 1/COLP钙调节蛋白-1抗体
ab101056/Anti-BMP6 antibody
Anti-ACY 3/HCV-HCBP1丙型肝炎病毒核结合蛋白-1抗体
Anti-CHRNA7烟碱型乙酰胆碱受体α7抗体
Anti-Cadherin 9钙粘附蛋白9抗体
ab101056/Anti-BMP6 antibody
ab100970/Anti-GAG antibody
ab104000/Anti-C9orf78 antibody
ab104225/Anti-FOX3/NeuN antibody
ab104031/Anti-CCDC42 antibody
Anti-JAK2蛋白质酪氨酸激酶JAK2抗体
Anti-MID2/RNF60/Midline-2环指蛋白60抗体"
本页产品地址：http://www.geilan.com/sell/show-3244990.html