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3260 VRK3 Antibody #3260

会员指数: 企业认证:

价格:电议

所在地:上海

型号:3260

更新时间:2013-07-29

浏览次数:624

公司地址:

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产品简介

"上海博耀生物销售VRK3 Antibody #3260,CST原装品质,价格优惠,订购VRK3 Antibody #3260,详情请咨询销售人员!产品详细参数如

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"上海博耀生物销售VRK3 Antibody #3260,CST原装品质,价格优惠,订购VRK3 Antibody #3260,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:VRK3 Antibody #3260
货号:3260
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
3260S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W H M R Mk Endogenous 54 Rabbit
Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: VRK3 Antibody detects endogenous levels of total VRK3 protein.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human VRK3. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:

The vaccinia-related kinase (VRK) proteins are a new group of Ser/Thr kinases in the human kinome. This mammalian kinase family comprises three members, VRK1, VRK2, and VRK3 (1-3). The VRK1 has autophosphorylation activity and phosphorylates several transcription factors, including p53 (4), ATF2 (5), and c-Jun (6). VRK2 is associated with the endoplasmic reticulum (7). VRK3 suppresses Erk activity through direct interaction and activation of the MAP kinase phosphatase VHR (8). Further functional and structural analysis of VRK proteins will elucidate important new aspects of cell regulation.

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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