3089 IRS-2 (L1326) Antibody #3089

"上海博耀生物销售IRS-2 (L1326) Antibody #3089，CST原装品质，价格优惠，订购IRS-2 (L1326) Antibody #3089，详情请咨询销售人

"上海博耀生物销售IRS-2 (L1326) Antibody #3089，CST原装品质，价格优惠，订购IRS-2 (L1326) Antibody #3089，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：IRS-2 (L1326) Antibody #3089
货号：3089
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3089S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H M R	Endogenous	185	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： IRS-2 (L1326) Antibody detects endogenous levels of total IRS-2 protein. It does not cross-react with IRS-1.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu1326 of human IRS-2. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Insulin Receptor Substrate 2 (IRS-2) is one of the major substrates of the insulin receptor kinase (1). In vertebrates, IRS-2 functions as a scaffolding protein to coordinate separate branches of the Insulin/IGF-signaling cascades (2). IRS-2 is essential for normal nutrient homeostasis because it mediates both peripheral insulin action and the effect of IGF-1 on B-cell growth. Mice lacking IRS-2 fail to maintain sufficient compensatory insulin secretion and develop diabetes as young adults (3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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