3088 TH1L Antibody #3088

"上海博耀生物销售TH1L Antibody #3088，CST原装品质，价格优惠，订购TH1L Antibody #3088，详情请咨询销售人员！产品详细参数如

"上海博耀生物销售TH1L Antibody #3088，CST原装品质，价格优惠，订购TH1L Antibody #3088，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：TH1L Antibody #3088
货号：3088
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3088S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H M R Mk (Hm) (C) (X) (B) (Dg) (Pg) (GP) (Hr)	Endogenous	66	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat  Hm=Hamster  Mk=Mon key  C=Chicken  X=Xenopus  B=Bovine  Dg=Dog  Pg=Pig  GP=Guinea Pig  Hr=Horse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： TH1L Antibody recognizes endogenous levels of total TH1L protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala132 of human TH1L protein. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Negative Elongation Factor (NELF) consists of four subunits: WHSC2 (NELF-A), COBRA-1 (NELF-B), TH1L (NELF-C/D), and NELF-E (1). NELF, together with DRB-sensitivity inducing factor (DSIF), inhibits RNA Polymerase II (RNAPII) elongation resulting in RNAPII promoter proximal pausing, where it awaits additional signaling to resume transcription (2,3). The release of this promoter proximal pausing of RNAPII is a critical regulatory point during transcription and is signaled by phosphorylation of the C-terminal domain (CTD) within the largest subunit of RNAPII and NELF by positive transcription elongation factor (P-TEFb) (4,5). WHSC2 is thought to connect the NELF complex to RNAPII machinery, while NELF-E contains an RNA binding motif that is necessary for NELF function (1,6,7). TH1L, together with COBRA-1, help bring WHSC2 and NELF-E together and are integral subunits of the NELF complex (1).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab102621/Anti-DOK6 antibody
ab101268/Anti-GC1q R antibody
Anti-FAM71AFAM71A蛋白抗体
ab103472/Anti-CD75 antibody
ab10419/Anti-FGF basic antibody
Anti-NK-2R神经激肽A受体/K物质受体抗体
Anti-NGFR/p75NTR神经生长因子受体抗体
Anti-GPA/GYPA/CD235a血型糖蛋白A/涎糖蛋白抗体
Anti-PSCA前列腺干细胞抗原抗体
Anti-RRADRRAD抗体
Anti-Lamin B2核纤层蛋白B2抗体
ab103488/Anti-CARD8 antibody
ab102994/Anti-FCHO1 antibody
ab103192/Anti-GAGE7 antibody
Anti-Substance PP物质抗体
ab10420/Anti-FGF basic antibody"
本页产品地址：http://www.geilan.com/sell/show-3244838.html