2942 FAAH1 (L14B8) Mouse mAb #2942

"上海博耀生物销售FAAH1 (L14B8) Mouse mAb #2942，CST原装品质，价格优惠，订购FAAH1 (L14B8) Mouse mAb #2942，详情请咨询销售

"上海博耀生物销售FAAH1 (L14B8) Mouse mAb #2942，CST原装品质，价格优惠，订购FAAH1 (L14B8) Mouse mAb #2942，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：FAAH1 (L14B8) Mouse mAb #2942
货号：2942
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： Monoclonal
规格：

No.	Size	Price
2942S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP	H M	Endogenous	60	Mouse IgG1

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： FAAH1 (L14B8) Mouse mAb detects endogenous levels of total FAAH1 protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence of human FAAH1.
抗体背景：

Endogenous cannabinoids have been implicated in addictive behaviors and drug abuse (1). Fatty-acid amide hydrolase 1 (FAAH1) is a plasma membrane-bound hydrolase that converts oleamide to oleic acid (2). This hydrolase also converts the cannabinoid anandamide, the endogenous ligand for the CB1 cannabinoid receptor, to arachidonic acid, suggesting a role in fatty-acid amide inactivation (2). Mice lacking FAAH1 have significantly higher levels of anandamide in the brain and show decreased sensitivity to pain, further indicating a role for FAAH1 in the regulation of endocannabinoid signaling in vivo (3). FAAH1 null mice also demonstrate an increased preference for alcohol and an increased voluntary uptake of alcohol as compared to wild-type mice, indicating a role of FAAH1 in modulating addictive behaviors (1).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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