2960 Histone H4 (L64C1) Mouse mAb (ChIP Formulated) #2960

"上海博耀生物销售Histone H4 (L64C1) Mouse mAb (ChIP Formulated) #2960，CST原装品质，价格优惠，订购Histone H4 (L64C1) Mou

"上海博耀生物销售Histone H4 (L64C1) Mouse mAb (ChIP Formulated) #2960，CST原装品质，价格优惠，订购Histone H4 (L64C1) Mouse mAb (ChIP Formulated) #2960，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Histone H4 (L64C1) Mouse mAb (ChIP Formulated) #2960
货号：2960
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： Monoclonal
规格：

No.	Size	Price
2960S	100 ul (5 immunoprecipitations)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
ChIP	H (M) (R) (Mk) (Dm) (X) (Z) (B) (Hr) (Ce)	Endogenous	11	Mouse IgG

Applications Key:  ChIP=Chromatin IP
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  Dm=D. melanogaster  X=Xenopus  Z=Zebrafish  B=Bovine  Hr=Horse  Ce=C. elegans
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Histone H4 (L64C1) Mouse mAb detects endogenous levels of total histone H4 protein. The antibody does not cross-react with other histones.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino-terminal sequence of human histone H4.
抗体背景：

Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin (1). The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination (2-5). These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression (6). In most species, histone H2B is primarily acetylated at Lys5, 12, 15, and 20 (4,7). Histone H3 is primarily acetylated at Lys9, 14, 18, 23, 27, and 56. Acetylation of H3 at Lys9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms (2,3). Phosphorylation at Ser10, Ser28, and Thr11 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis (8-10). Phosphorylation at Thr3 of histone H3 is highly conserved among many species and is catalyzed by the kinase haspin. Immunostaining with phospho-specific antibodies in mammalian cells reveals mitotic phosphorylation at Thr3 of H3 in prophase and its dephosphorylation during anaphase (11).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab104200/Anti-EXOC6 antibody
ab102625/Anti-CHCHD1 antibody
ab101557/Anti-ABHD10 antibody
Anti-MAG-a/L-MAG髓鞘相关糖蛋白-a抗体
Anti-Annexin V重组膜粘连蛋白5抗体
Anti-ADRB2肾上腺素能受体β2抗体（β2-AR ）
ab102843/Anti-Ext2 antibody
Anti-Laminin alpha 5层粘蛋白α5抗体
ab103666/Anti-EPDR1 antibody
ab103608/Anti-CCDC21 antibody
ab103315/Anti-BASP1 antibody
Anti-CKLFSF2 isoform 1趋化素样因子超家族成员2亚型1抗体
ab101009/Anti-CRMP4 antibody
Anti-SOCS3细胞因子信号传导抑制蛋白3抗体
ab10366/Anti-GRO beta antibody
ab101964/Anti-C1orf104 antibody"
本页产品地址：http://www.geilan.com/sell/show-3244729.html