2866 Survivin (71G4B7) Rabbit mAb (Alexa Fluor 647 Conjugate) #2866

"上海博耀生物销售Survivin (71G4B7) Rabbit mAb (Alexa Fluor 647 Conjugate) #2866，CST原装品质，价格优惠，订购Survivin (71

"上海博耀生物销售Survivin (71G4B7) Rabbit mAb (Alexa Fluor 647 Conjugate) #2866，CST原装品质，价格优惠，订购Survivin (71G4B7) Rabbit mAb (Alexa Fluor 647 Conjugate) #2866，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Survivin (71G4B7) Rabbit mAb (Alexa Fluor 647 Conjugate) #2866
货号：2866
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2866S	100 ul (50 tests)	询价

抗体应用：

Applications	Reactivity	Sensitivity	Isotype
F	H M R	Endogenous	Rabbit IgG

Applications Key:  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Survivin (71G4E) Rabbit mAb (Alexa Fluor^® 647 Conjugate) detects endogenous levels of total survivin protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding cysteine 60 of human survivin. The antibody was conjugated to Alexa Fluor^® 647 under optimal conditions with an F/P ratio of 2-6. The Alexa Fluor^® 647 dye is maximally excited by red light (e.g. 633 nm He-Ne laser). Antibody conjugates of the Alexa Fluor^® 647 dye produce bright far-red-fluorescence emission, with a peak at 665 nm.
抗体背景：

Survivin is a 16 kDa anti-apoptotic protein highly expressed during fetal development and cancer cell malignancy (1). Survivin binds and inhibits caspase-3, controlling the checkpoint in the G2/M-phase of the cell cycle by inhibiting apoptosis and promoting cell division (2,3). This regulatory process requires the phosphorylation of survivin at Thr34 by p34 cdc2 kinase (4). Gene targeting using a Thr34 phosphorylation-defective survivin mutant, as well as antisense survivin, have been shown to inhibit tumor growth (5,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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