2848 Vav2 (C64H2) Rabbit mAb #2848

"上海博耀生物销售Vav2 (C64H2) Rabbit mAb #2848，CST原装品质，价格优惠，订购Vav2 (C64H2) Rabbit mAb #2848，详情请咨询销售

"上海博耀生物销售Vav2 (C64H2) Rabbit mAb #2848，CST原装品质，价格优惠，订购Vav2 (C64H2) Rabbit mAb #2848，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Vav2 (C64H2) Rabbit mAb #2848
货号：2848
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2848P	40 ul (4 western blots)	询价
2848S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP	H Mk	Endogenous	100	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Vav2 (C64H2) Rabbit mAb detects endogenous levels of total Vav2 protein. The antibody is not expected to cross-react with Vav1 or Vav3 based on the sequence of the immunogenic peptide.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Vav2.
抗体背景：

Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian Vav proteins (Vav1, Vav2 and Vav3) differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. Vav2 and Vav3 are more ubiquitously expressed. Vav proteins contain the Dbl homology domain, which confers GEF activity, as well as protein interaction domains that allow them to function in pathways regulating actin cytoskeleton organization (reviewed in 1). Phosphorylation stimulates the GEF activity of Vav protein towards Rho/Rac (2,3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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