2844 Phospho-C/EBPalpha (Thr222/226) Antibody #2844

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"上海博耀生物销售Phospho-C/EBPalpha (Thr222/226) Antibody #2844，CST原装品质，价格优惠，订购Phospho-C/EBPalpha (Thr222/226) Antibody #2844，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-C/EBPalpha (Thr222/226) Antibody #2844
货号：2844
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2844S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M (R)	Endogenous	30, 42, 45	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-C/EBPalpha (Thr222/226) Antibody detects endogenous levels of C/EBPalpha only when phosphorylated at threonine 222 and 226. This antibody does not cross-react with other phosphorylated C/EBP isoforms.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr222/226 of mouse C/EBPalpha. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

CCAAT/enhancer-binding proteins (C/EBPs) are a family of transcription factors that are critical for cellular differentiation, terminal function, and inflammatory response (1). Six members of the family have been characterized (C/EBPα, β, δ, γ, ε, and ζ) and are distributed in a variety of tissues (1). Translation from alternative start codons results in two isoforms of C/EBPα (p42 and p30), which are both strong transcriptional activators (2). It has been reported that insulin and insulin-like growth factor-I stimulate the dephosphorylation of C/EBPα, which may play a key role in insulin-induced repression of GLUT4 transcription (3). Phosphorylation of C/EBPα at Thr222, Thr226, and Ser230 by GSK-3 seems to be required for adipogenesis (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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