产品简介
"上海博耀生物销售Oct-4A (C30A3) Rabbit mAb #2840,CST原装品质,价格优惠,订购Oct-4A (C30A3) Rabbit mAb #2840,详情请咨询
产品说明
"上海博耀生物销售
Oct-4A (C30A3) Rabbit mAb #2840,CST原装品质,价格优惠,订购
Oct-4A (C30A3) Rabbit mAb #2840,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:Oct-4A (C30A3) Rabbit mAb #2840
货号:2840
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Monoclonal
规格:
| No. |
Size |
Price |
| 2840P |
40 ul (4 western blots) |
询价 |
| 2840S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Isotype |
| W IF-IC F |
H M |
Endogenous |
45 |
Rabbit IgG |
Applications Key:
W=Western Blotting
IF-IC=Immunofluorescence (Immunocytochemistry)
F=Flow Cytometry
Reactivity Key:
H=Human
M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
Oct-4A (C30A3) Rabbit mAb detects endogenous levels of total Oct-4A protein.
来源及纯化方法:
Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human Oct-4A.
抗体背景:
Oct-4 (POU5F1) is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells (1). A network of key factors that includes Oct-4, Nanog, and Sox2 is necessary for the maintenance of pluripotent potential, and downregulation of Oct-4 has been shown to trigger cell differentiation (2,3). Research studies have demonstrated that Oct-4 is a useful germ cell tumor marker (4). Oct-4 exists as two splice variants, Oct-4A and Oct-4B (5). Recent studies have suggested that the Oct-4A isoform has the ability to confer and sustain pluripotency, while Oct-4B may exist in some somatic, non-pluripotent cells (6,7).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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