2778 SH2D1A Antibody #2778

"上海博耀生物销售SH2D1A Antibody #2778，CST原装品质，价格优惠，订购SH2D1A Antibody #2778，详情请咨询销售人员！产品详细参

"上海博耀生物销售SH2D1A Antibody #2778，CST原装品质，价格优惠，订购SH2D1A Antibody #2778，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：SH2D1A Antibody #2778
货号：2778
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2778S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H	Endogenous	14	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： SH2D1A Antibody detects endogenous levels of total SH2D1A protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues around Gly112 of human SH2D1A. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

SH2D1A and SH2D1B are small, adaptor proteins with a single SH2-domain that play important signal transduction roles mediated by the signaling lymphocytic activation molecule (SLAM) family receptors (1). SH2D1A (also called SAP or SLAM-associated protein) is frequently mutated in patients with X-linked lymphoproliferative disease (Duncan’s disease), which is characterized by extreme susceptibility to Epstein-Barr virus; approximately 50 different SH2D1A mutations have been reported to date (2-4). The single SH2D1B gene in humans (also called EAT-2 or Ewing's sarcoma's/FLI1-activated transcript 2) is present as a pair of duplicated EAT-2A and EAT-2B genes with identical genomic organization in mouse and rat (5,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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