2775 LC3B Antibody #2775

"上海博耀生物销售LC3B Antibody #2775，CST原装品质，价格优惠，订购LC3B Antibody #2775，详情请咨询销售人员！产品详细参数如

"上海博耀生物销售LC3B Antibody #2775，CST原装品质，价格优惠，订购LC3B Antibody #2775，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：LC3B Antibody #2775
货号：2775
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2775S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IF-IC F	H M R (Mk) (B) (Pg)	Endogenous	14, 16	Rabbit

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  B=Bovine  Pg=Pig
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： LC3B detects endogenous levels of total LC3B protein. Cross-reactivity may exist with other LC3 isoforms. Stronger reactivity is observed with the type II form of LC3B.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of LC3B. Antibodies were purified by peptide affinity chromatography.
抗体背景：

Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents (1,2). Autophagy is generally activated by conditions of nutrient deprivation, but it has also been associated with a number of physiological processes including development, differentiation, neurodegenerative diseases, infection, and cancer (3). Autophagy marker Light Chain 3 (LC3) was originally identified as a subunit of microtubule-associated proteins 1A and 1B (termed MAP1LC3) (4) and subsequently found to contain similarity to the yeast protein Apg8/Aut7/Cvt5 critical for autophagy (5). Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy (6-9). Cleavage of LC3 at the carboxy terminus immediately following synthesis yields the cytosolic LC3-I form. During autophagy, LC3-I is converted to LC3-II through lipidation by a ubiquitin-like system involving Atg7 and Atg3 that allows for LC3 to become associated with autophagic vesicles (6-10). The presence of LC3 in autophagosomes and the conversion of LC3 to the lower migrating form, LC3-II, have been used as indicators of autophagy (11).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab102663/Anti-C1 Inactivator antibody
Anti-PKA/PKAcat/PKACB蛋白激酶A抗体
ab104304/Anti-cPLA2 beta antibody
Anti-FAM83FFAM83F蛋白抗体
Anti-AEBP1脂肪细胞增强结合蛋白1
Anti-CNTN4/AXCAM轴突相关粘附分子抗体
Anti-CD144/VECD/VE Cadherin上皮型钙粘附分子抗体
Anti-VAP1血管粘附蛋白1抗体
ab103152/Anti-Granzyme B antibody
ab102815/Anti-GAA antibody
Anti-GM-CSF粒细胞-巨噬细胞克隆刺激因子抗体
Anti-OCT1阳离子转运器1抗体
ab103667/Anti-beta II Tubulin antibody
Anti-CRPC-反应蛋白抗体
Anti-MDM2双微体2癌基因抗体
Anti-Mesothelin间皮素抗体"
本页产品地址：http://www.geilan.com/sell/show-3244577.html