2771 DYRK1A Antibody #2771

"上海博耀生物销售DYRK1A Antibody #2771，CST原装品质，价格优惠，订购DYRK1A Antibody #2771，详情请咨询销售人员！产品详细参

"上海博耀生物销售DYRK1A Antibody #2771，CST原装品质，价格优惠，订购DYRK1A Antibody #2771，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：DYRK1A Antibody #2771
货号：2771
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2771S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H M (R)	Endogenous	90	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： DYRK1A Antibody detects endogenous levels of total DYRK1A protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human DYRK1A. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

The DYRK family includes several dual-specificity tyrosine-phosphorylated and regulated kinases capable of phosphorylating proteins at both Tyr and Ser/Thr residues (1). The DYRK family was identified based on homology to the yeast Yak1 (2) and the Drosophila minibrain (mnb) kinases (3). Seven mammalian isoforms have been discovered, including DYRK1A, DYRK1B, DYRK1C, DYRK2, DYRK3, DYRK4, and DYRK4B. Differences in substrate specificity, expression, and subcellular localization are seen across the DYRK family (4,5). All DYRK proteins have a Tyr-X-Tyr motif in the catalytic domain activation loop; phosphorylation of the second Tyr residue (e.g. Tyr312 of DYRK1A) is necessary for kinase activity. DYRKs typically autophosphorylate the Tyr residue within their activation loop, but phosphorylate substrates at Ser and Thr residues (1,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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