2714 Lck (V49) Antibody #2714

"上海博耀生物销售Lck (V49) Antibody #2714，CST原装品质，价格优惠，订购Lck (V49) Antibody #2714，详情请咨询销售人员！产品

"上海博耀生物销售Lck (V49) Antibody #2714，CST原装品质，价格优惠，订购Lck (V49) Antibody #2714，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Lck (V49) Antibody #2714
货号：2714
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2714S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H	Endogenous	56	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Lck (V49) Antibody detects endogenous levels of total Lck protein. This antibody does not cross-react with other src family proteins.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val49 of human Lck. Antibodies are purified by peptide affinity chromatography.
抗体背景：

The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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