2704 Phospho-Zap-70 (Tyr493) Antibody #2704

"上海博耀生物销售Phospho-Zap-70 (Tyr493) Antibody #2704，CST原装品质，价格优惠，订购Phospho-Zap-70 (Tyr493) Antibody #27

"上海博耀生物销售Phospho-Zap-70 (Tyr493) Antibody #2704，CST原装品质，价格优惠，订购Phospho-Zap-70 (Tyr493) Antibody #2704，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-Zap-70 (Tyr493) Antibody #2704
货号：2704
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2704S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP F	H (M) (R)	Endogenous	70	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-Zap-70 (Tyr493) Antibody detects endogenous levels of Zap-70 only when phosphorylated at Tyr493.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr493 of human Zap-70. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement (1). Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck (2-6). Tyrosine phosphorylation correlates with increased Zap-70 kinase activity and downstream signaling events. Expression of Zap-70 is correlated with disease progression and survival in patients with chronic lymphocytic leukemia (7,8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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