2444 eIF4H Antibody #2444

"上海博耀生物销售eIF4H Antibody #2444，CST原装品质，价格优惠，订购eIF4H Antibody #2444，详情请咨询销售人员！产品详细参数

"上海博耀生物销售eIF4H Antibody #2444，CST原装品质，价格优惠，订购eIF4H Antibody #2444，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：eIF4H Antibody #2444
货号：2444
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2444S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IF-IC	H M R Mk	Endogenous	25, 27	Rabbit

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： eIF4H Antibody detects endogenous levels of total eIF4H protein (both long and short isoforms).
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to a sequence of human eIF4H. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

A variety of factors contribute to the initiation of translation. Eukaryotic translation initiation factor 4H (eIF4H) was purified to near homogeneity from rabbit reticulocyte lysate and shown to stimulate translation in an assay deficient in eIF4F and eIF4B (1). eIF4H induces the RNA-dependent ATP hydrolysis catalyzed by the initiation factors eIF4A and eIF4B (1,2). eIF4H was further shown to stimulate the initial rate and extent of eIF4A-mediated mRNA secondary structure unwinding (3). Interaction between eIF4H and the herpes simplex virus shutoff protein (Vhs) appears to be important for Vhs-mediated degradation of mRNA (4). Deletion of a large region of chromosome 7, including the corresponding eIF4H gene, results in Williams-Beuren Syndrome (WBS), an autosomal dominant disorder that can present with cardiovascular problems, mental retardation and distinctive facial features (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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