2413 Rab11a Antibody #2413

"上海博耀生物销售Rab11a Antibody #2413，CST原装品质，价格优惠，订购Rab11a Antibody #2413，详情请咨询销售人员！产品详细参

"上海博耀生物销售Rab11a Antibody #2413，CST原装品质，价格优惠，订购Rab11a Antibody #2413，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Rab11a Antibody #2413
货号：2413
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2413S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IF-IC	H M R Mk	Endogenous	25	Rabbit

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Rab11a Antibody detects endogenous levels of total Rab11a protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg184 of human Rab11a protein. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Rab11a, Rab11b and Rab25 are members of the Rab11 family of small Ras-like GTPases. Rab11 (isoforms Rab11a and Rab11b) functions as a key regulator in the recycling of perinuclear, plasma membrane and Golgi compartment endosomes (1,2). Despite some overlap, distinct differences exist between Rab11a and Rab11b in both their cellular distribution and functional roles. Rab11a is ubiquitously expressed while Rab11b is found mainly in the heart and brain (3,4). Like other Rab proteins, Rab11 exerts its function via interactions with Rab11 family interacting proteins (FIPs). While there are three distinct classes of FIPs, all appear to share a conserved carboxy-terminal Rab-binding domain that allows Rab-FIP protein interaction. When bound together, these proteins are thought to regulate membrane-associated protein sorting (5,6).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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