2192 Presenilin 2 Antibody #2192

"上海博耀生物销售Presenilin 2 Antibody #2192，CST原装品质，价格优惠，订购Presenilin 2 Antibody #2192，详情请咨询销售人员

"上海博耀生物销售Presenilin 2 Antibody #2192，CST原装品质，价格优惠，订购Presenilin 2 Antibody #2192，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Presenilin 2 Antibody #2192
货号：2192
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2192P	40 ul (4 western blots)	询价
2192S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H M R Mk	Endogenous	23 (C-terminal fragment). 54 (full-length).	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Presenilin 2 Antibody detects endogenous levels of the carboxy-terminal fragment of presenilin 2 (23 kDa) and the full length protein (54 kDa) to a lesser extent. It does not cross-react with endogenous levels of presenilin 1.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding amino acid 330 of human presenilin 2. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer disease, probably due to presenilin's associated γ-secretase activity for amyloid-β protein processing (1,2). Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed amino-terminal (34 kDa) and carboxy-terminal (~20, 22, 23 kDa) fragments (CTF) (2,3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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