2178 PGC-1α (3G6) Rabbit mAb #2178

"上海博耀生物销售PGC-1α (3G6) Rabbit mAb #2178，CST原装品质，价格优惠，订购PGC-1α (3G6) Rabbit mAb #2178，详情请咨询销

"上海博耀生物销售PGC-1α (3G6) Rabbit mAb #2178，CST原装品质，价格优惠，订购PGC-1α (3G6) Rabbit mAb #2178，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：PGC-1α (3G6) Rabbit mAb #2178
货号：2178
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2178S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W	H	Transfected Only	130	Rabbit IgG

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： PGC-1α (3G6) Rabbit mAb detects transfected levels of total PGC-1α protein. This antibody does not cross-react with PGC-1β or other related proteins.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with recombinant human PGC-1α fusion protein.
抗体背景：

PPARγ coactivator-1α (PGC-1α) was originally identified as a transcriptional coactivator whose expression closely correlated with adaptive thermogenesis following exposure to cold temperatures (1). Named for its association with the nuclear receptor peroxisome-proliferator activated receptor (PPARγ), PGC-1α interacts with a diverse array of transcription factors to regulate numerous aspects of cell physiology (2). PGC-1α helps to regulate cell processes important in adaptive thermogenesis and energy metabolism, including the related functions of glucose uptake, gluconeogenesis, insulin secretion, and mitochondrial biogenesis (3). Long thought to be a potential therapeutic target for the treatment of type II diabetes, obesity, cardiomyopathy, or other metabolic disorders (reviewed in 4), a recent functional survey found no obvious differences in PPARγ activity associated with recognized PGC-1α variants (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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