2175 Cyclophilin A Antibody #2175

"上海博耀生物销售Cyclophilin A Antibody #2175，CST原装品质，价格优惠，订购Cyclophilin A Antibody #2175，详情请咨询销售人

"上海博耀生物销售Cyclophilin A Antibody #2175，CST原装品质，价格优惠，订购Cyclophilin A Antibody #2175，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Cyclophilin A Antibody #2175
货号：2175
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2175S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Mk (B) (Dg)	Endogenous	18	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  B=Bovine  Dg=Dog
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Cyclophilin A Antibody detects endogenous levels of total Cyclophilin A protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of Cyclophilin A. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Cyclophilins are a highly conserved family of peptidylprolyl cis-trans-isomerases (PPIA) that are targets of the immunosuppressant drug cyclosporin A (CsA) (1,2). The complex of cyclophilin and CsA can bind to and inhibit calcineurin which leads to inhibition of the transcription factor NFAT and decreased production of cytokines (3,4). As isomerases, cyclophilins have been proposed to aid in protein folding. Cyclophilin A can bind to the p55 Gag protein of HIV and appears necessary for HIV infection (5,6). There is also some evidence that cyclophilins have nuclease activity and play a role in apoptosis (7).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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