产品简介
"上海博耀生物销售Phospho-Lamin A/C (Ser22) Antibody #2026,CST原装品质,价格优惠,订购Phospho-Lamin A/C (Ser22) Antibody
产品说明
"上海博耀生物销售
Phospho-Lamin A/C (Ser22) Antibody #2026,CST原装品质,价格优惠,订购
Phospho-Lamin A/C (Ser22) Antibody #2026,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:Phospho-Lamin A/C (Ser22) Antibody #2026
货号:2026
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Polyclonal
规格:
| No. |
Size |
Price |
| 2026S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W IF-IC |
H M R |
Endogenous |
69, 78 |
Rabbit |
Applications Key:
W=Western Blotting
IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:
H=Human
M=Mouse
R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
Phospho-Lamin A/C (Ser22) Antibody detects endogenous levels of lamin A/C only when phosphorylated at Ser22.
来源及纯化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser22 of human lamin A/C protein.
抗体背景:
Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3,4). The cleavage of lamins results in nuclear disregulation and cell death (5,6).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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