JN0289 重组人趋化因子CXCL4

我公司致力于为客户提供高纯度、低成本的活性重组蛋白，包括重组人趋化因子CXCL4在内的各类受体、细胞因子、生长因子、转录因子、激素、酶、毒性蛋白、病毒抗原等。...

特别提示：包括重组人趋化因子CXCL4(PF4)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人趋化因子CXCL4(PF4)
英文名称：Recombinant Human C-X-C Motif Chemokine 4
产品货号：JN0289
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备，目的基因编码的Glu32-Ser101表达纯化而来。

CXCL4/PF4质量控制：＞95%(还原性SDS-PAGE)。

CXCL4/PF4制剂：冻干品

CXCL4/PF4保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CXCL4/PF4复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CXCL4/PF4：
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokine receptor CXCR3, known as CXCR3B. The major physiologic role of CXCL4 appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. In contrast to other CXC chemokines, CXCL4 lacks chemotactic activity for polymorphonuclear granulocytes.

根据您的关注的重组人趋化因子CXCL4(PF4)，重组C-X-C Motif Chemokine 4，rPF4，重组PF4，重组人趋化因子CXCL4，重组人C-X-C Motif Chemokine 4，重组趋化因子CXCL4，重组人PF4，rhPF4，Recombinant Human C-X-C Motif Chemokine 4，您可能还对以下产品有需求：



名称：重组人白介素IL-20(白细胞介素20)
货号：JN0356
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Leu25-Glu176表达纯化而来。

IL-20质量控制：＞95%(还原性SDS-PAGE)。

IL-20制剂：冻干品

IL-20保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-20复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-20：
Interleukin-20 (IL-20) is a member of the IL-10 family of regulatory cytokines that includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 exhibits approximately 28% amino acid identity with IL-10 and 76% amino acid identity with mouse IL-20. There are two heterodimeric receptor complexes for IL-20. The first is composed of IL-20 Rα and IL-20 Rβ. The second is composed of IL-22 R and IL-20 Rβ. Whereas the IL-22 R/IL-20 Rβ complex is shared with IL-24, the IL-20 Rα/IL-20 Rβ complex is shared with both IL-19 and IL-24. IL-20 has been shown to initiate transduction cascades involving STAT3 and stimulates the induction of pro-inflammatory genes including TNF-α and MCP-1. Initial functional studies using transgenic mice suggest that IL-20 has the ability to regulate skin development. The over-expression of both human and mouse forms of IL-20 results in keratinocyte hyper-proliferation, abnormal epidermal differentiation, and neonatal lethality. In humans, IL-20 and its receptors are up-regulated in psoriatic skin, and polymorphisms in the IL-20 gene have been associated with plaque-type psoriasis. IL-20 may also have a role in hematopoiesis. It enhances the proliferation of multi-potential progenitors in vitro and increases their numbers and cell cycling status in IL-20 transgenic mice. IL-20 is also shown to suppress COX-2 and PGE2 and acts as an inhibitor of angiogenesis in model systems.

关注重组人趋化因子CXCL4(PF4)，重组C-X-C Motif Chemokine 4，rPF4，重组PF4，重组人趋化因子CXCL4，重组人C-X-C Motif Chemokine 4，重组趋化因子CXCL4，重组人PF4，rhPF4，Recombinant Human C-X-C Motif Chemokine 4的同时，为您推荐更多您可能感兴趣的产品：


JN0375 重组人白介素10受体β(Fc Tag) 10μg|50μg|500μg|1mg
JN0584 重组人MICA 10μg|50μg|500μg|1mg
JN0641 重组人促肾上腺皮质激素释放因子结合蛋白(CRHBP)(CRFBP) 10μg|50μg|500μg|1mg
JN0781 重组人维生素D结合蛋白(VDBP) 10μg|50μg|500μg|1mg
JN0837 重组人PROC(蛋白酶K依赖性蛋白C) 10μg|50μg|500μg|1mg
JN1182 重组猕猴SYT1 10μg|50μg|500μg|1mg
JN1318 重组小鼠ANGPTL4(血管生成素样蛋白4) 10μg|50μg|500μg|1mg

如果您觉得“JN0289 重组人趋化因子CXCL4”描述资料不够齐全，请联系我们获取详细资料。(联系时请告诉我从给览网看到的，我们将给您最大优惠！)
本页链接：http://www.geilan.com/com_bjbiolab/sell/itemid-8551355.html
已经有877位访客查看了本页.