JN0495 重组人CD30(TNFRSF8)

我公司致力于为客户提供高纯度、低成本的活性重组蛋白，包括重组人CD30(TNFRSF8)在内的各类受体、细胞因子、生长因子、转录因子、激素、酶、毒性蛋白、病毒抗原等。...

特别提示：包括重组人CD30(TNFRSF8)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人CD30(TNFRSF8)
英文名称：Recombinant Human Tumor necrosis factor receptor superfamily member 8
产品货号：JN0495
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Phe19-Lys379在C端带有Fc标签。

CD30/TNFRSF8质量控制：＞95%(还原性SDS-PAGE)

CD30/TNFRSF8制剂：冻干品

CD30/TNFRSF8保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD30/TNFRSF8复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD30/TNFRSF8：
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.

根据您的关注的重组人CD30(TNFRSF8)，Recombinant Human Tumor necrosis factor receptor superfamily member 8，重组CD30，重组Tumor necrosis factor receptor superfamily member 8，重组人Tumor necrosis factor receptor superfamily member 8，rCD30，rhCD30，重组人TNFRSF8，rhTNFRSF8，rTNFRSF8，重组人CD30，重组TNFRSF8，您可能还对以下产品有需求：

货号	名称	规格
JN0245	重组人VEGF-A(血管内皮生长因子A)(带His标签)	10μg|50μg|500μg|1mg
JN0264	重组人(小鼠成纤维生长因子8B)	10μg|50μg|500μg|1mg
JN0275	重组小鼠转换生长因子β2(TGF-β2)	10μg|50μg|500μg|1mg
JN0315	重组小鼠趋化因子CXCL16(SR-PSOX)	10μg|50μg|500μg|1mg
JN1993	重组人真核翻译起始因子1A,X染色体(EIF1AX)	10μg|50μg|500μg|1mg
JN0558	重组人AMIGO3	10μg|50μg|500μg|1mg

关注重组人CD30(TNFRSF8)，Recombinant Human Tumor necrosis factor receptor superfamily member 8，重组CD30，重组Tumor necrosis factor receptor superfamily member 8，重组人Tumor necrosis factor receptor superfamily member 8，rCD30，rhCD30，重组人TNFRSF8，rhTNFRSF8，rTNFRSF8，重组人CD30，重组TNFRSF8的同时，为您推荐更多您可能感兴趣的产品：



名称：重组人白介素IL-12(白细胞介素12)
货号：JN0399
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Arg23-Ser219&Ile23-Ser328表达纯化而来。

IL-12质量控制：＞95%(还原性SDS-PAGE)。

IL-12制剂：冻干品

IL-12保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-12复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-12：
IL-12 is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit.Human and mouse IL‑12 share 70% and 60% amino acid sequence identity in their p40 and p35 subunits, respectively. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-γ. T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.

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