YT723 兔抗HER2/ErbB2抗体

兔抗HER2/ErbB2抗体是高品质的一抗产品，由北京百奥莱博供应，本产品仅用于生物化学研究方面，兔抗HER2/ErbB2抗体是我司众多优质一抗之一，质量堪比同类进口产品，价格非常优惠，目前正热烈促销中，恭候您的咨询订购。...

特别提示：包括兔抗HER2/ErbB2抗体在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：兔抗HER2/ErbB2抗体
英文名称：HER2/ErbB2 Rabbit Polyclonal Antibody
产品货号：YT723
产品规格：50μl

本品为来源于兔的抗HER2/ErbB2的多克隆抗体。
宿主：兔
克隆性：多克隆抗体
用途：WB,ICC, IHC,IF
交叉反应性：人
分子量：140KDa
推荐稀释比例：WB(1:500-1:1000),IF(1:200),IHC(1:200),ICC(1:200)

about this Antibody
Name	HER2/ErbB2 Rabbit Polyclonal Antibody
Category	Polyclonal antibody(pAb); Primary antibody
Isotype	IgG
Purification	Peptide affinity purified
about the Immunogen
Immunogen	This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to human ErbB2.
Gene ID	2064
SwissProt	P04626
Synonyms	CerbB2 antibody; CerbB2/neu protein antibody; ErbB2 antibody; HER2 antibody
Category	RTK
Background	HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or overexpression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approx. 30% of breast cancer patients. Over-expression is also known to occur in ovarian, stomach, and aggressive forms of uterine cancer, such as uterine serous endometrial carcinoma. The expression of HER2 is regulated by signaling through estrogen receptors. Normally, estradiol and tamoxifen acting through the estrogen receptor down-regulate the expression of HER2. However, when the ratio of the coactivator AIB-3 exceeds that of the corepressor PAX2, the expression of HER2 is upregulated in the presence of tamoxifen, leading to tamoxifen-resistant breast cancer.

注意事项：
1. 如果本抗体用于Western blot (WB)、免疫荧光(IF)、免疫细胞化学(ICC)等实验，请注意回收使用过的稀释抗体。回收的抗体通常至少可以重复使用5-10次。稀释后的抗体，包括已经使用过的稀释抗体，请4℃保存。
2. 回收后重复使用的抗体，使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象，可以10,000g离心1-3分钟，取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况，则可以考虑废弃该抗体。
3. 提供的Western一抗稀释液也可以用于免疫荧光(IF)、免疫组化(IHC)、免疫细胞化学(ICC)等适当用途。如果希望获得zuì佳的检测效果，请考虑使用上述检测专用的一抗稀释液。

储存条件：-20℃，有效期一年。

根据您的关注的兔抗HER2/ErbB2抗体，兔抗HER2/ErbB2抗体，YT723，百奥莱博，，，您可能还对以下产品有需求：



名称：小鼠抗Ku70抗体
货号：YT735
规格：50μl
本品为来源于小鼠的抗Ku70的单克隆抗体。
宿主：小鼠
克隆性：单克隆抗体
用途：WB,IHC
交叉反应性：人，小鼠
分子量：70KDa
推荐稀释比例：WB(1:1000),IHC(1:50-1:100)

about this Antibody
Name	Ku70 Mouse Monoclonal Antibody
Category	Monoclonal antibody(mAb); Primary antibody
Isotype	IgG2a
Purification	ProA affinity purified
about the Immunogen
Immunogen	This antibody is produced by immunizing mice with a recombinant protein corresponding to a region of Ku70.
Gene ID	2547
SwissProt	P12956
Synonyms	70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; ATP-dependent DNA helicase II, 70 kDa subunit; CTC box binding factor 75 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF
Category	Cell Cycle / Checkpoint Control
Background	Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system.In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein.

注意事项：
1. 如果本抗体用于Western blot (WB)、免疫荧光(IF)、免疫细胞化学(ICC)等实验，请注意回收使用过的稀释抗体。回收的抗体通常至少可以重复使用5-10次。稀释后的抗体，包括已经使用过的稀释抗体，请4℃保存。
2. 回收后重复使用的抗体，使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象，可以10,000g离心1-3分钟，取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况，则可以考虑废弃该抗体。
3. 提供的Western一抗稀释液也可以用于免疫荧光(IF)、免疫组化(IHC)、免疫细胞化学(ICC)等适当用途。如果希望获得zuì佳的检测效果，请考虑使用上述检测专用的一抗稀释液。

储存条件：-20℃，有效期一年。

关注兔抗HER2/ErbB2抗体，兔抗HER2/ErbB2抗体，YT723，百奥莱博，，的同时，为您推荐更多您可能感兴趣的产品：

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