JN1502 重组小鼠TIM-3

我公司致力于为客户提供高纯度、低成本的活性重组蛋白，包括重组小鼠TIM-3在内的各类受体、细胞因子、生长因子、转录因子、激素、酶、毒性蛋白、病毒抗原等。

北京百奥莱博科技有限公司是一家专业的生物试剂销售公司。公司主要经营血清、抗原、抗体等生物试剂产品，可以为您提供专业的技术服务，以优良的价格、优质的服务、优先的理念，满足客户的各方面的需求，与国内多家企业、单位建立了良好的长期合作关系，拥有较好的企业信誉和品牌形象。

特别提示：包括重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)
英文名称：Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3
产品货号：JN1502
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg20-Arg191在C端含有His标签。

TIM-3 质量控制：＞95%(还原性SDS-PAGE)

TIM-3 制剂：冻干品

TIM-3 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TIM-3 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TIM-3 ：
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.

根据您的关注的重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)，重组小鼠TIM-3，重组TIM-3，rTIM-3，重组小鼠T cell Immunoglobulin and Mucin Domain-3，重组T cell Immunoglobulin and Mucin Domain-3，Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3，rmTIM-3，重组T细胞免疫球蛋白黏蛋白分子3，重组小鼠T细胞免疫球蛋白黏蛋白分子3，您可能还对以下产品有需求：



名称：重组人β-NGF(β神经生长因子)
货号：JN0261
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Ser122-Arg239表达纯化而来。

beta-NGF质量控制：＞95%(还原性SDS-PAGE)。

beta-NGF制剂：冻干品

beta-NGF保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

beta-NGF复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于beta-NGF：
Human β-Nerve Growth Factor (β-NGF) was initially isolated in the mouse submandibular gland. It is composed of three non-covalently linked subunits α, β, and γ; it exhibits all the biological activities ascribed to NGF. It is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. Β-NGF is a neurotrophic factor that signals through its receptor β-NGF, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. These results suggest that β-NGF is a pleiotropic cytokine, which in addition to its neurotropic activities may have an important role in the regulation of the immune system. Human β-NGF shares 90% sequence similarity with mouse protein and shows cross-species reactivity.

关注重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)，重组小鼠TIM-3，重组TIM-3，rTIM-3，重组小鼠T cell Immunoglobulin and Mucin Domain-3，重组T cell Immunoglobulin and Mucin Domain-3，Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3，rmTIM-3，重组T细胞免疫球蛋白黏蛋白分子3，重组小鼠T细胞免疫球蛋白黏蛋白分子3的同时，为您推荐更多您可能感兴趣的产品：

货号	名称	规格
JN0241	重组人HDGF(肝癌衍生生长因子)	10μg|50μg|500μg|1mg
JN0317	重组人趋化因子CCL18(PARC)	10μg|50μg|500μg|1mg
JN0385	重组小鼠白介素IL-33(白细胞介素33)	10μg|50μg|500μg|1mg
JN1953	重组人视网醇结合蛋白4(RBP4)	10μg|50μg|500μg|1mg
JN2013	重组人CDK4抑制剂C(CDKN2C)	10μg|50μg|500μg|1mg
JN0883	重组人泛素样蛋白(ISG15)	10μg|50μg|500μg|1mg

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