特别提示:包括重组人激活素受体IIA(激活素IIA型受体)(Activin受体IIA)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人激活素受体IIA(激活素IIA型受体)(Activin受体IIA)
英文名称:Recombinant Human Activin Receptor Type-2A
产品货号:JN1079
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala20-Pro134在C端含有Fc标签和His标签
Activin RIIA质量控制:>95%(还原性SDS-PAGE)
Activin RIIA制剂:冻干品
Activin RIIA保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Activin RIIA复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Activin RIIA:
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threo
nine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for ex
pression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are co
nsidered to be co
nstitutively active kinases.
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