特别提示:包括重组人IDH1在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人IDH1
英文名称:Recombinant Human Isocitrate Dehydrogenase [NADP] Cytoplasmic
产品货号:JN1475
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Leu414在C端带His标签。
IDH1质量控制:>95%(还原性SDS-PAGE)
IDH1制剂:液体
IDH1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于IDH1:
Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belo
ngs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause me
taphyseal cho
ndromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the co
nversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that co
nsume 2-oxoglutarate, namely the α-hydroxylation of phytanic acid.
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