JN1912 重组人BH3结构域凋亡诱导蛋白

我公司致力于为客户提供高纯度、低成本的活性重组蛋白，包括重组人BH3结构域凋亡诱导蛋白在内的各类受体、细胞因子、生长因子、转录因子、激素、酶、毒性蛋白、病毒抗原等。

北京百奥莱博科技有限公司是一家专业的生物试剂销售公司。公司主要经营血清、抗原、抗体等生物试剂产品，可以为您提供专业的技术服务，以优良的价格、优质的服务、优先的理念，满足客户的各方面的需求，与国内多家企业、单位建立了良好的长期合作关系，拥有较好的企业信誉和品牌形象。 主营产品:血清、抗体、抗原、核酸提取、核酸纯化等生化试剂

特别提示：包括重组人BH3结构域凋亡诱导蛋白(BID)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人BH3结构域凋亡诱导蛋白(BID)
英文名称：Recombinant Human BH3-Interacting Domain Death Agonist
产品货号：JN1912
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Asp195表达纯化得来。

BID/BH3-interacting domain death agonist质量控制：＞95%(还原性SDS-PAGE)

BID/BH3-interacting domain death agonist制剂：液体

BID/BH3-interacting domain death agonist保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于BID/BH3-interacting domain death agonist：
BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint.

根据您的关注的重组人BH3结构域凋亡诱导蛋白(BID)，重组BH3结构域凋亡诱导蛋白，rhBID，重组BID，重组人BH3结构域凋亡诱导蛋白(BID)，重组人BID，重组人BH3-Interacting Domain Death Agonist，重组人BH3结构域凋亡诱导蛋白，重组BH3-Interacting Domain Death Agonist，rBID，Recombinant Human BH3-Interacting Domain Death Agonist，BID，JN1912，百奥莱博，，，您可能还对以下产品有需求：

货号	名称	规格
JN0241	重组人HDGF(肝癌衍生生长因子)	10μg|50μg|500μg|1mg
JN0336	重组人白介素IL-15(白细胞介素15)	10μg|50μg|500μg|1mg
JN0597	重组人ULBP-2(N2DL2)	10μg|50μg|500μg|1mg
JN0685	重组人肽酰脯氨酰顺反异构酶1(PPIase)	10μg|50μg|500μg|1mg
JN0766	重组人PRKG1(依赖于cGMP的蛋白激酶)(cGMP依赖性蛋白激酶)	10μg|50μg|500μg|1mg
JN0877	重组人自噬相关蛋白质3	10μg|50μg|500μg|1mg

关注重组人BH3结构域凋亡诱导蛋白(BID)，重组BH3结构域凋亡诱导蛋白，rhBID，重组BID，重组人BH3结构域凋亡诱导蛋白(BID)，重组人BID，重组人BH3-Interacting Domain Death Agonist，重组人BH3结构域凋亡诱导蛋白，重组BH3-Interacting Domain Death Agonist，rBID，Recombinant Human BH3-Interacting Domain Death Agonist，BID，JN1912，百奥莱博，，的同时，为您推荐更多您可能感兴趣的产品：



名称：重组人睫状神经营养因子(CNTF)
货号：JN0656
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ala2-Met200表达纯化得来。

CNTF质量控制：＞95%(还原性SDS-PAGE)

CNTF制剂：冻干品

CNTF保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CNTF复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CNTF：
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.


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