特别提示:包括重组人IL-35在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人IL-35
英文名称:Recombinant Human Interleukin-35
产品货号:JN1532
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Arg21-Lys229&Arg23-Ser219在C端带有Fc标签。
IL-35质量控制:>80%(还原性SDS-PAGE)
IL-35制剂:冻干品
IL-35保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
IL-35复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于IL-35:
Interleukin-35 is a newest and potent suppressive cytokine of the IL-12 family. Unlike other members of the IL-12 family which are produced mainly by antigen-presenting cells (APCs), IL-35 has been identified as a potentially immunosuppressive cytokine primarily produced by regulatory T (Treg) cells, and to a lesser extent by activated dendritic cells and macrophages. IL-35 is composed of the IL-12 p35 subunit and the IL-27 Epstein–Barr virus-induced protein 3 (EBI3) subunit. IL-35 plays an im
portant role in many disease models and has been recently shown to have additio
nal functions aside from inhibition of proliferation, including inducing its own ex
pression in non-Treg cells.
根据您的关注的
重组人IL-35,Recombinant Human Interleukin-35,重组人IL-35,rhInterleukin-35,rInterleukin-35,重组人Interleukin-35,重组Interleukin-35,JN1532,百奥莱博,,,您可能还对以下产品有需求:
名称:重组小鼠4-1BB Ligand(TNFSF9)
货号:JN0510
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Arg104-Glu309在N端带有His标签。
4-1BB Ligand/TNFSF9质量控制:>95%(还原性SDS-PAGE)
4-1BB Ligand/TNFSF9制剂:冻干品
4-1BB Ligand/TNFSF9保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
4-1BB Ligand/TNFSF9复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于4-1BB Ligand/TNFSF9:
Tumor necrosis factor ligand superfamily member 9, also known as 4-1BBL, is a member of the the tumor necrosis factor family. Mouse 4-1BBL cDNA encodes a 309 amino acid residues (aa) protein with an 82 aa N-terminal cytoplasmic domain, a 21 aa transmembrane domain and a 206 aa C-terminal extracellular domain. The extracellular domain of 4-1BBL has a tertiary structure similar to that of other TNFSF members, but shares o
nly low aa sequence homology (14-16%). 4-1BBL is predominantly expressed on activated antigen presenting cells (APCs) such as B cells, macrophages and dendritic cells (DCs). It is also expressed on most T and B lymphoma cell lines. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 respo
nses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.
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关注
重组人IL-35,Recombinant Human Interleukin-35,重组人IL-35,rhInterleukin-35,rInterleukin-35,重组人Interleukin-35,重组Interleukin-35,JN1532,百奥莱博,,的同时,为您推荐更多您可能感兴趣的产品:
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