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价格:电议
所在地:北京
型号:YT755
手机:18518407031(微信同步)
电话:18518407031
更新时间:2023-05-23
浏览次数:1395
公司地址:北京市海淀区紫雀路33号院3号楼
特别提示:包括兔抗Ras抗体在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
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a |
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| Name |
Ras Rabbit Polyclo |
| Category |
Polyclo |
| Isotype | IgG |
| Purification | Peptide affinity purified |
|
a |
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| Immunogen |
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) correspo |
| Gene ID | 4893/3265/3845 |
| SwissProt | P01111/P01112/P01116 |
|
Syno |
GTPase NRas; Transforming protein N-Ras; NRAS; HRAS1; GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras; HRAS; HRAS1; GTPase KRas; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras; KRAS; KRAS2; RASK2 |
| Category | - |
| Background |
Ras superfamily is a protein superfamily of small GTPases, which are all related, to a degree, to the Ras protein subfamily (the key human members of which are KRAS, NRAS, and HRAS). Receptor tyrosine kinases and G protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway. GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, research studies have shown that in 30% of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common o |
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