特别提示:包括重组人前列腺素D2合成酶(PTGDS)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人前列腺素D2合成酶(PTGDS)
英文名称:Recombinant Human Prostaglandin-D2 Synthase
产品货号:JN0671
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala23-Gln190在C端含有His标签。
PTGDS质量控制:>95%(还原性SDS-PAGE)
PTGDS制剂:液体
PTGDS保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PTGDS:
Prostaglandin-H2 D-Isomerase (PTGDS) belo
ngs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyzes the co
nversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. PTGDS binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. It possibly participates in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor, blood-testis barrier, the central nervous system and male reproductive system.
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