特别提示:包括重组人u-Plasminogen Activator在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人u-Plasminogen Activator
英文名称:Recombinant Human Urokinase-Type Plasminogen Activator
产品货号:JN0547
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser21-Leu431在C端含有His标签。
u-Plasminogen Activator质量控制:>95%(还原性SDS-PAGE)
u-Plasminogen Activator制剂:液体
u-Plasminogen Activator保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于u-Plasminogen Activator:
Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and me
tastasis in many human cancers associated with breast, co
lon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-l
inked two-chain molecule. There exists two forms A chain, the long A chain co
ntains an EGF-like domain that is respo
nsible for binding of the uPA receptor. The B chain correspo
nds to the catalytic domain.
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