特别提示:包括重组人B型钠尿肽(NPPB)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人B型钠尿肽(NPPB)
英文名称:Recombinant Human Natriuretic Peptides B
产品货号:JN1946
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的His27-His134在N端含有His标签。
NPPB质量控制:>95%(还原性SDS-PAGE)
NPPB制剂:液体
NPPB保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于NPPB:
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.
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名称:重组人白介素IL-4(白细胞介素4)
货号:JN0392
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备,目的基因编码的His25-Ser153在C端含有His标签。
IL-4质量控制:>95%(还原性SDS-PAGE)。
IL-4制剂:冻干品
IL-4保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-4复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-4:
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell respo
nses including cell proliferation, survival and gene ex
pression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
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