特别提示:包括重组人TSLP(胸腺基质淋巴细胞生成素)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人TSLP(胸腺基质淋巴细胞生成素)
英文名称:Recombinant Human Thymic stromal lymphopoietin
产品货号:JN1392
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Tyr29-Gln159表达纯化得来。
TSLP质量控制:>95%(还原性SDS-PAGE)
TSLP制剂:冻干品
TSLP保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
TSLP复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于TSLP:
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP (159 aa) and sfTSLP (63 aa) produced by alternative splicing . lfTSLP (159aa) is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral mucosa, skin and in salivary glands. In aa sequence level, Human TSLP displays a
bout 43% identity with mouse TSLP. Thymic stromal lymphopoietin (TSLP) is a cytokine that functions mainly on myeloid cells; it induces the release of T cell-attracting chemokines from mo
nocytes and enhances the maturation of CD11c(+) dendritic cells . TSLP has proliferative effects on the myeloid cell line and may initiate asthma or atopic dermatitis respo
nses by directly activating mast cells . TSLP signals cells via the interleukin-7 receptor-α chain (IL-7Rα), shared with IL-7, together with the TSLP receptor (TSLPR) subunit. Recent studies indicate that TSLP and its receptor are novel therapeutic targets for rheumatoid arthritis , for increased intraarticular TSLP co
ncentrations in patients has caused chemotaxis and activation of arthritogenic T cells.
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关注
重组人TSLP(胸腺基质淋巴细胞生成素),Recombinant Human Thymic stromal lymphopoietin,重组人TSLP,重组胸腺基质淋巴细胞生成素,胸腺基质淋巴细胞生成素,rTSLP,rhTSLP,重组人胸腺基质淋巴细胞生成素,重组Thymic stromal lymphopoietin,重组人TSLP(胸腺基质淋巴细胞生成素),重组TSLP,重组人Thymic stromal lymphopoietin,JN1392,百奥莱博,,的同时,为您推荐更多您可能感兴趣的产品:
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