JN0667 重组人血管非炎性分子2

我公司致力于为客户提供高纯度、低成本的活性重组蛋白，包括重组人血管非炎性分子2在内的各类受体、细胞因子、生长因子、转录因子、激素、酶、毒性蛋白、病毒抗原等。

北京百奥莱博科技有限公司是一家专业的生物试剂销售公司。公司主要经营血清、抗原、抗体等生物试剂产品，可以为您提供专业的技术服务，以优良的价格、优质的服务、优先的理念，满足客户的各方面的需求，与国内多家企业、单位建立了良好的长期合作关系，拥有较好的企业信誉和品牌形象。

特别提示：包括重组人血管非炎性分子2(Vanin-2)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人血管非炎性分子2(Vanin-2)
英文名称：Recombinant Human Vascular Non-Inflammatory Molecule 2
产品货号：JN0667
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln23-Ser492在C端含有His标签。

Vanin-2质量控制：＞95%(还原性SDS-PAGE)

Vanin-2制剂：冻干品

Vanin-2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Vanin-2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Vanin-2：
Vascular Non-Inflammatory Molecule 2 (VNN2) is a member of the CN hydrolase family. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. they possess pantetheinase activity, which may play a role in oxidative-stress response. VNN2 is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. VNN2 involved in the thymus homing of bone marrow cells. In addition, VNN2 may regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.

根据您的关注的重组人血管非炎性分子2(Vanin-2)，重组人血管非炎性分子2，重组血管非炎性分子2，重组Vascular Non-Inflammatory Molecule 2，Recombinant Human Vascular Non-Inflammatory Molecule 2，rVanin-2，Vanin-2，rhVanin-2，重组Vanin-2，重组人Vanin-2，重组人血管非炎性分子2(Vanin-2)，重组人Vascular Non-Inflammatory Molecule 2，JN0667，百奥莱博，，，您可能还对以下产品有需求：


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JN0361 重组人白介素22受体α2(IL-22Rα2) 10μg|50μg|500μg|1mg
JN0365 重组人白介素1受体辅助蛋白(Ser21-Gln356) 10μg|50μg|500μg|1mg
JN0394 重组人白介素IL-18(白细胞介素18) 10μg|50μg|500μg|1mg
JN0404 重组人组蛋白脱乙酰基酶10(HDAC10) 10μg|50μg|500μg|1mg
JN1955 重组人Stratifin蛋白 10μg|50μg|500μg|1mg

关注重组人血管非炎性分子2(Vanin-2)，重组人血管非炎性分子2，重组血管非炎性分子2，重组Vascular Non-Inflammatory Molecule 2，Recombinant Human Vascular Non-Inflammatory Molecule 2，rVanin-2，Vanin-2，rhVanin-2，重组Vanin-2，重组人Vanin-2，重组人血管非炎性分子2(Vanin-2)，重组人Vascular Non-Inflammatory Molecule 2，JN0667，百奥莱博，，的同时，为您推荐更多您可能感兴趣的产品：



名称：重组人趋化因子CXCL2(MIP-2)
货号：JN0298
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Thr39-Asn107表达纯化而来。

CXCL2/MIP-2质量控制：＞95%(还原性SDS-PAGE)。

CXCL2/MIP-2制剂：冻干品

CXCL2/MIP-2保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CXCL2/MIP-2复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CXCL2/MIP-2：
Chemokine Ligand 2 (CXCL2) is a small secreted cytokine which belongs to the CXC chemokine family. It is secreted by monocytes and macrophages and chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2. It has been known to regulate immune functions mainly by chemo-attracting neutrophils. It is produced by activated monocytes and neutrophils and expressed at sites of inflammation. It is a hematoregulatory chemokine, which suppresses hematopoietic progenitor cell proliferation. It can be induced by receptor activator of NF-kappaB ligand, the osteoclast (OC) differentiation factor, through JNK and NF-kappaB signaling pathways in OC precursor cells. CXCL2 in turn enhanced the proliferation of OC precursor cells of bone marrow-derived macrophages (BMMs) through the activation of ERK. Knockdown of CXCL2 inhibited both the proliferation of and the ERK activation in BMMs. During osteoclastogenesis CXCL2 stimulated the adhesion and the migration of BMMs. CXCL2 is a novel therapeutic target for inflammatory bone destructive diseases.

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