特别提示:包括重组人SIRPα(信号调节蛋白α)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人SIRPα(信号调节蛋白α)
英文名称:Recombinant Human Signal-Regulatory Protein alpha 1
产品货号:JN1824
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Glu31-Arg370在C端含有His标签。
SIRPA质量控制:>95%(还原性SDS-PAGE)
SIRPA制剂:冻干品
SIRPA保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
SIRPA复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于SIRPA:
Signal Regulatory Protein α (SIRPα) is a mo
nomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα co
ntains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRPα shows adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. SIRPα engagement generally produces a negative regulatory signal; it may mediate negative regulation of phagocytosis, mast cell activation and dendritic cell activation
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重组人SIRPα(信号调节蛋白α),重组人Signal-Regulatory Protein alpha 1,重组信号调节蛋白α,Recombinant Human Signal-Regulatory Protein alpha 1,rhSIRPα,重组Signal-Regulatory Protein alpha 1,信号调节蛋白α,重组SIRPα,重组人信号调节蛋白α,重组人SIRPα,rSIRPα,重组人SIRPα(信号调节蛋白α),JN1824,百奥莱博,,,您可能还对以下产品有需求:
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重组人SIRPα(信号调节蛋白α),重组人Signal-Regulatory Protein alpha 1,重组信号调节蛋白α,Recombinant Human Signal-Regulatory Protein alpha 1,rhSIRPα,重组Signal-Regulatory Protein alpha 1,信号调节蛋白α,重组SIRPα,重组人信号调节蛋白α,重组人SIRPα,rSIRPα,重组人SIRPα(信号调节蛋白α),JN1824,百奥莱博,,的同时,为您推荐更多您可能感兴趣的产品:
名称:重组人白介素8(IL-8)(Ala23-Ser99)
货号:JN0287
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Ala23-Ser99表达纯化而来。
IL-8/CXCL8质量控制:>95%(还原性SDS-PAGE)。
IL-8/CXCL8制剂:冻干品
IL-8/CXCL8保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-8/CXCL8复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-8/CXCL8:
Interleukin-8 (IL-8) belo
ngs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in respo
nse to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the o
nset of a variety of disease states.
名称:重组人白介素IL-13(白细胞介素13)
货号:JN0378
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备,目的基因编码的Leu25-Asn146在C端含有His标签。
IL-13质量控制:>95%(还原性SDS-PAGE)。
IL-13制剂:冻干品
IL-13保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-13复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-13:
Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II ex
pression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.
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