特别提示:包括重组人TIMP-1(金属蛋白酶1组织抑制剂)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人TIMP-1(金属蛋白酶1组织抑制剂)
英文名称:Recombinant Human Tissue Inhibitor of me
talloproteinases 1
产品货号:JN1692
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Cys24-Ala207在C端含有His标签。
TIMP-1质量控制:>95%(还原性SDS-PAGE)
TIMP-1制剂:冻干品
TIMP-1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
TIMP-1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于TIMP-1:
Tissue Inhibitor of me
talloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix me
talloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. Timp-1 complexes with me
talloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of o
nly human and murine erythroid progenitors. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16, without MMP-14.
根据您的关注的
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talloproteinases 1,rTIMP-1,重组TIMP-1,金属蛋白酶1组织抑制剂,重组Tissue Inhibitor of me
talloproteinases 1,重组人TIMP-1(金属蛋白酶1组织抑制剂),rhTIMP-1,Recombinant Human Tissue Inhibitor of me
talloproteinases 1,重组人TIMP-1,JN1692,百奥莱博,,,您可能还对以下产品有需求:
名称:重组小鼠RANK(TNFRSF11A)(CD265)
货号:JN0509
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Val31-Ser214在C端含有His标签。
RANK/TNFRSF11A/CD265质量控制:>95%(还原性SDS-PAGE)
RANK/TNFRSF11A/CD265制剂:冻干品
RANK/TNFRSF11A/CD265保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
RANK/TNFRSF11A/CD265复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于RANK/TNFRSF11A/CD265:
Receptor activator of NF-κB(RANK,TNFRSF11A) belo
ngs to one member oftumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, brain and kidney, but weakly expressed in spleen and bone marrow. After binding its ligand RANKL, RANK can activate signaling pathways such as NF-κB, JNK, ERK, p38, and Akt/PKB, through TRAF protein phosphorylation. RANK/TNFRSF11A signaling is largely co
nsidered to be growth promoting and apoptosis reducing such as the effects observed in osteoclasts. RANK/TNFRSF11A was also found to be involved in the regulation of interactions between T-cells and dendritic cells.
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重组人TIMP-1(金属蛋白酶1组织抑制剂),重组人金属蛋白酶1组织抑制剂,重组金属蛋白酶1组织抑制剂,重组人Tissue Inhibitor of me
talloproteinases 1,rTIMP-1,重组TIMP-1,金属蛋白酶1组织抑制剂,重组Tissue Inhibitor of me
talloproteinases 1,重组人TIMP-1(金属蛋白酶1组织抑制剂),rhTIMP-1,Recombinant Human Tissue Inhibitor of me
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