SC-7863 DR4 (H-130)抗体

抗体 名：DR4 (H-130)抗体

规格：200ug

Santa Cruz是美国也是上zui大的抗体生产厂家，提供抗体种类多达两万多种，几乎覆盖了目前生命科学研究的各个新领域，其每种抗体又有多个克隆可选择，并有对应蛋白标准品及相关产品，为免疫学研究工作提供了大的方便。
产品介绍：

DR4 (H-130)抗体基因信息：

Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes FAS antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the “death domain,” that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including FAS , DR2 (or TRUNDD), DR3 (Death Receptor 3), DR4 and DR5. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. A non-death domain-containing receptor, designated decoy receptor (DcR1 or TRID), also specifically associates with TRAIL and may play a role in cellular resistance to apoptotic stimuli.