3353 Phospho-Stathmin (Ser16) Antibody #3353

"上海博耀生物销售Phospho-Stathmin (Ser16) Antibody #3353，CST原装品质，价格优惠，订购Phospho-Stathmin (Ser16) Antibody #

"上海博耀生物销售Phospho-Stathmin (Ser16) Antibody #3353，CST原装品质，价格优惠，订购Phospho-Stathmin (Ser16) Antibody #3353，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-Stathmin (Ser16) Antibody #3353
货号：3353
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
3353S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R Hm Mk	Endogenous	19, 20	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Hm=Hamster  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-Stathmin (Ser16) Antibody recognizes endogenous levels of stathmin protein only when phosphorylated at Ser16.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser16 of human stathmin. Antibodies are purified using protein A and peptide affinity chromatography.
抗体背景：

Stathmin is a ubiquitously expressed microtubule destabilizing phosphoprotein that is upregulated in a number of cancers. The amino terminus of the protein contains multiple phosphorylation sites and is involved in the promotion of tubulin filament depolymerization. Phosphorylation at these sites inactivates the protein and stabilizes microtubules. Ser16 phosphorylation by CaM kinases II and IV (1,2) increases during G2/M-phase and is involved in mitotic spindle regulation (3,4). Ser38 is a target for cdc2 kinase (5) and TNF-induced cell death gives rise to reactive oxygen intermediates leading to hyperphosphorylation of stathmin (6). EGF receptor activation of Rac and cdc42 also increases phosphorylation of stathmin on Ser16 and Ser38 (7). Other closely related family members are neuronally expressed and include SCG10, SCLIP, RB3 and its splice variants RB3' and RB3''. Stathmin and SCG10 have been shown to play roles in neuronal-like development in PC12 cells (8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab10413/Anti-CSN1 antibody
Anti-PCDHGA11原钙粘蛋白γA11抗体
Anti-Leptin瘦素抗体
Anti-Beta-arrestin 1β-抑制蛋白1抗体
Anti-CD105/EndoglinCD105抗体
ab101533/Anti-CD43 antibody
Anti-Tau protein微管相关蛋白抗体
ab101682/Anti-Cdk2 antibody
ab103469/Anti-DLL4 antibody
Anti-CDK7周期素依赖性激酶7抗体
ab102952/Anti-CCDC98 antibody
ab101681/Anti-Alas1 antibody
ab10237/Anti-cardiac Troponin I antibody
Anti-IRS-2胰岛素受体底物-2抗体
Anti-SPRR1a/Cornifin A角质蛋白α抗体
Anti-NRP1/CD304神经纤毛蛋白1抗体"
本页产品地址：http://www.geilan.com/sell/show-3245090.html